| Course title | Molecular Biology |
|---|---|
| Course code | KMB/250 |
| Organizational form of instruction | Lecture + Seminary |
| Level of course | Bachelor |
| Year of study | not specified |
| Frequency of the course | In each academic year, in the winter semester. |
| Semester | Winter |
| Number of ECTS credits | 5 |
| Language of instruction | Czech |
| Status of course | Compulsory, Compulsory-optional |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Lecturer(s) |
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| Course content |
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Content of lectures 1. Structure of the nucleic acids and proteins, structure of the genome, central dogma of molecular biology. 2. Replication of DNA in prokaryotes and eukaryotes. 3. Transcription in prokaryotes and eukaryotes 4. Regulation of transcription in prokaryotes 5. Regulation of transcription in eukaryotes 6. Splicing, transport, stability and editing of RNA, non-coding RNA 7. Proteins synthesis, genetic code, prions. 8. Structure of proteins, posttranslational modification. 9. Viruses, transposones. 10. Mutations, repair of DNA. 11. Basic methods of molecular biology. 12. Genomics. The powerpoint presentations from the course will be available online, the textbooks Molecular Biology from Clark and Pazdernik are available in the academic library.
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| Learning activities and teaching methods |
Monologic (reading, lecture, briefing), Dialogic (discussion, interview, brainstorming), Projection
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| Learning outcomes |
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The goal of this course is to make students familiar with the principles of the genetic code and with the basic mechanisms of storing, expression and modification of genetic information
Student will understand the basic principles of molecular biology, in particular the molecular processes behind DNA replication, transcription, protein translation and reparation of DNA. Emphasis will be given to the understanding of regulatory mechanisms behind these processes both in prokaryotes and eukaryotes. Part of each lecture will be devoted to the principles of basic methods of molecular biology, like PCR, sequencing, gel electrophoresis, restriction analysis, RNA interference, Crispr/Cas9 and others. |
| Prerequisites |
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Participants of the course are expected to have a secondary school knowledge of chemistry and cell biology.
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| Assessment methods and criteria |
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Essay, Test
As a requirement for 'zapocet' the participants of the course are asked to take part of a miniconference regarding Nobel prize winners from the field of molecular biology. Student will make their own presentations to explain the key experiments that lead to the discoveries. It is strongly recommended to attend the lectures although it is not a compulsory requirement for the admission to the final test. |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Science | Study plan (Version): Biology (1) | Category: Biology courses | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Secondary Schools Teacher Training in Biology (1) | Category: Pedagogy, teacher training and social care | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Biophysics (1) | Category: Physics courses | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Biomedical Laboratory Techniques (1) | Category: Biology courses | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Education | Study plan (Version): Biology Education (1) | Category: Pedagogy, teacher training and social care | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Experimental Biology (1) | Category: Biology courses | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Biology for future teachers (1) | Category: Biology courses | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Education | Study plan (Version): Biology Education (1) | Category: Pedagogy, teacher training and social care | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Secondary Schools Teacher Training in Biology (1) | Category: Pedagogy, teacher training and social care | - | Recommended year of study:-, Recommended semester: Winter |