| Course title | Biochemistry 1 |
|---|---|
| Course code | UCH/757 |
| Organizational form of instruction | Lecture + Seminary |
| Level of course | Bachelor |
| Year of study | not specified |
| Frequency of the course | In each academic year, in the winter semester. |
| Semester | Winter |
| Number of ECTS credits | 4 |
| Language of instruction | English |
| Status of course | Compulsory |
| Form of instruction | unspecified |
| Work placements | unspecified |
| Recommended optional programme components | None |
| Course availability | The course is available to visiting students |
| Lecturer(s) |
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| Course content |
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1) Composition of organisms, biogenic compounds, prokaryotes and eukaryotes their characterization and composition, organelles and their origin, biological macromolecules, noncovalent interactions, basic concept of metabolism 2) Introduction to metabolism, catabolism, anabolism, oxidation, electron carriers, role of ATP, substrate phosphorylation, energy in Coenzyme A 3) Sugars, classification, structure, function, cyclisation, glycosidic bond, reactions - reducing sugars, oligosaccharides, polysaccharides, structure and function, glycoconjugates, extra cellular matrix 4) Lipids, characterization and function, lipids without fatty acids, fatty acids and their role in physical and chemical properties of lipids, lipid hormones, fat and oils, membrane lipids, branched lipids 5) Biological membranes, composition, function, membrane rafts, membrane transport, signalization, membrane pumps, Na/K concept 6) Amino acids, structure, properties, AK metabolites in organism, peptide bond, peptides and proteins, methods of isolation, sequencing, structure determination 7) Structure of proteins, Ramachandran plot, primary, secondary, tertiary, quaternary structure, globular and fibrous proteins, posttranslational modification 8) Protein function, Hemoglobin, antibodies, actin and myosin, keratin, collagen, fibroin 9) Nucleic acids, nucleotides and nucleosides, bases, DNA and RNA, structure and function, central dogma, chemical modification of nucleotides 10) Enzymes, function, kinetics, nomenclature, inhibition
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| Learning activities and teaching methods |
Monologic (reading, lecture, briefing), Dialogic (discussion, interview, brainstorming), Work with text (with textbook, with book), Work with multi-media resources (texts, internet, IT technologies)
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| Learning outcomes |
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Course aims at introduction of general biochemistry for students of the Biological Chemistry bachelor study programme. The course provides a broad array of fundamental knowledge of structural and functional biochemistry which are essential for understanding of other subjects in Biological Chemistry curriculum. In the course framework, biochemistry is given as chemistry of non-binding/non-covalent interactions which take place in biological systems on the level of molecules and cells. Structural and functional properties of the components which play a role in the transmission of energy as well as signals are emphasized.
Students will gain knowledge of the basics of biochemistry and must pass a test. |
| Prerequisites |
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Basic knowledge of general, inorganic, organic chemistry and cell biology.
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| Assessment methods and criteria |
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Oral examination
Students must correctly answer at least 50 % questions. |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Science | Study plan (Version): Biological Chemistry (1) | Category: Chemistry courses | 2 | Recommended year of study:2, Recommended semester: Winter |