Course: Optical Spectroscopy

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Course title Optical Spectroscopy
Course code UFY/455
Organizational form of instruction Lecture + Practice
Level of course Master
Year of study not specified
Frequency of the course In each academic year, in the summer semester.
Semester Summer
Number of ECTS credits 6
Language of instruction Czech
Status of course Compulsory, Compulsory-optional
Form of instruction unspecified
Work placements unspecified
Recommended optional programme components None
Course availability The course is available to visiting students
Lecturer(s)
  • Polívka Tomáš, prof. RNDr. Ph.D.
  • Litvín Radek, doc. RNDr. Ph.D.
  • Bína David, RNDr. Ph.D.
Course content
The course focuses on introducing optical spectroscopy methods, including the theoretical foundation of individual methods and their application, particularly for studying biological and biochemical systems. Lectures are supplemented with practical exercises demonstrating the use of individual methods. Content: 1. Radiation, light-matter interaction, absorption, emission, scattering 2. Radiation sources, detection methods, principles, applications 3. Methods based on light scattering by macromolecules, DLS 4. Absorption spectroscopy 5. Linear and circular dichroism 6. Fluorescence 1, fundamentals of the method: excitation emission spectra, fluorophores, FRET 7. Fluorescence 2, time-resolved fluorescence, fluorescence correlation spectroscopy 8. Vibrational methods, introduction 9. Infrared spectroscopy, FTIR 10. Raman spectroscopy methods, resonance Raman spectroscopy 11. Ultrafast spectroscopy: transient absorption, photon echo, two-dimensional spectroscopy (optional) 12. Optical microscopy, confocal microscopy, localization, high resolution

Learning activities and teaching methods
Monologic (reading, lecture, briefing), Demonstration, Laboratory
  • Class attendance - 52 hours per semester
  • Preparation for exam - 50 hours per semester
  • Preparation for classes - 50 hours per semester
Learning outcomes
This course introduces methods of optical spectroscopy used primarily for the study of organic molecules and biological systems. Lecturer will demonstrate the theoretical fundamentals and the methods were applied at limit frontier of theoretical availability. Instrumentation is involved in practicals.
Students intensify their knowledge of optics, optical instrumentation techniques and methods used primarily for biological and biochemical materials.
Prerequisites
Basic knowledge of Physics III topics (wave and particle nature of light, interference and diffraction, wave theory, refraction index and polarization)
UFY/CV013
----- or -----
UFY/437

Assessment methods and criteria
Oral examination, Development of laboratory protocols

Part of the course Optical Spectroscopy is a regular, one-week, practice. All protocols on practices are required. Oral exam.
Recommended literature
  • Gilbert, A., J. Baggott. Essentials of Molecular Photochemistry, 1991..
  • H. van Amerongen et al.: Photosynthetic Excitons, 2000..
  • P. W. Atkins: Physical Chemistry..
  • P.W. Atkins: Molecular Quantum Mechanics..
  • Atkins, P. W.; De Paula, Julio; Bartovská, Lidmila; Cibulka, Ivan,; Dohnal, Vladimír,; Chuchvalec, Pavel,; Kania, Patrik,; Kolafa, Jiří,; Kratochvíl, Bohumil,; Malijevský, Alexandr; Matějka, Pavel,; Řehák, Karel,; Slavíček, Petr,; Tkadlecová, Marcela. Fyzikální chemie. Vydání první. Praha : Vysoká škola chemicko-technologická v Praze, 2013. ISBN 978-80-7080-830-6.
  • Lakowicz, Joseph R. Principles of fluorescence spectroscopy. 2nd ed. New York : Kluwer, 1999. ISBN 0-306-46093-9.
  • Prosser, Václav. Experimentální metody biofyziky. Vydání 1. Praha : Academia, 1989. ISBN 80-200-0059-3.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester