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Lecturer(s)
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Kulich Ivan, Mgr. Ph.D.
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Krejčí Alena, RNDr. Ph.D.
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Drutovic David, RNDr. Ph.D.
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Mozgová Iva, Mgr. Ph.D.
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Jindra Marek, prof. RNDr. CSc.
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Bruce Alexander William, prof. Ph.D.
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Course content
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Content of lectures: 1. Introduction: developmental biology - historical perspective, tools and models 2. Cell identity specification, maintenance and reprogramming 3. Molecular signalling in development - signal perception and transduction 4. Drosophila: Gene and pathway discovery and the genetic toolkit (Marek Jindra - BC AVČR - 9% per lecture) 5. Signalling in insect development: Drosophila and beyond (Marek Jindra - BC AVČR - 9% per lecture) 6. Cell signalling during early mammalian development I (Alex Bruce - PřF JČU - 9% per lecture) 7. Cell signalling during early mammalian development II (Alex Bruce - PřF JČU - 9% per lecture) 8. Plants: apical meristems and postembryonic body plan establishment - where is the germline? 9. Plants: hormonal regulation of plant development - auxin in the spotlight. 10. Plants: developmental transitions - when, where and how? 11. Concluding research lecture: guest lecture or discussion
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Learning activities and teaching methods
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unspecified
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Learning outcomes
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The course aims at providing understanding of general and organism-specific molecular mechanisms of developmental processes in multicellular organisms
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Prerequisites
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unspecified
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Assessment methods and criteria
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unspecified
Requirements on student: credit: student presentation (10 min) in the form of journal club: presentation of recent influential findings in developmental biology of selected (model) organism. exam: Oral or short answer written (min. 50 %).
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Recommended literature
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"Developmental Biology" by Scott Gilbert et al..
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For presentation ("journal club"), students will choose original research articles in combination with review articles published within the last 5 years.
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"Molecular Biology of the Cell" by Alberts et al..
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"Molecular Cell Biology" by Lodish et al..
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"Molecular Life of Plants" by Russel Jones et al..
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