|
Lecturer(s)
|
-
Petříček Miroslav, Ing. CSc.
|
|
Course content
|
Basic terms, roles of secondary metabolism, bioactive compounds. Antibiotics including resistance Biosynthesis of secondary metabolites, basic biosynthetic systems Secondary metabolites of plants, animals, metabolites affecting eukaryotic cells Genetics and regulation of antibiotic production Methodology - screening for novel bioactive compounds, historical and modern screening techniques including "omics" methods.
|
|
Learning activities and teaching methods
|
- Class attendance
- 26 hours per semester
- Preparation for classes
- 26 hours per semester
- Preparation for credit
- 10 hours per semester
- Semestral paper
- 15 hours per semester
|
|
Learning outcomes
|
To compile information on secondary metabolism of prokaryotes, fungi, animals and plants from various points of view, including methodology in their investigation and biotechnology applications.
|
|
Prerequisites
|
unspecified
|
|
Assessment methods and criteria
|
unspecified
|
|
Recommended literature
|
-
Comprehensive natural products II: Chemistry and biology, Mander, Lew; Liu, Hung-Wen (Ben) eds. 2010, 1st ed., Elsevier, Amsterdam.
-
Medicinal natural products: a biosynthetic approach / Paul M. Dewick. - 2nd ed., 2002, John Wiley & Sons, Inc., New York.
-
Natural Products from Plants, Second Edition; Leland J. Cseke, Ara Kirakosyan, Peter B. Kaufman, Sara Warber, James A. Duke, Harry L. Brielmann, 2006, CRC Press.
-
Případně recentní informace formou odborných článků dle vývoje v oboru. / Supplemented with a few journal articles reflecting recent achievements in the field..
|