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Lecturer(s)
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Šetlíková Irena, doc. RNDr. Ph.D.
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Berec Michal, doc. Mgr. Ph.D.
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Robovský Jan, RNDr. Ph.D.
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Course content
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Biochemical mechanisms of action of toxic substances, biotransformation of toxins in the organism. Examples of pharmacological effects in the organism. Cumulation of toxic substances in food chains. Possible effects of toxic effects of pesticides and other substances in plants and animals. Mycotoxins, potential source of feed intoxication. Microbial toxins. Plant toxins - overview, important groups with regard to plant species in collections and plants as a potential source of intoxication of "hobby" animals. Animal toxins: significance, enlargement, Invertebrate and Vertebrate toxins, their characteristics and specifics.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing), Excursion
- Class attendance
- 56 hours per semester
- Field trip
- 8 hours per semester
- Semestral paper
- 30 hours per semester
- Preparation for exam
- 56 hours per semester
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Learning outcomes
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The aim of the course is to acquaint students with the basics of toxicology with an overview of the main groups of microbial, plant, fungal and animal toxins, biochemical mechanisms of effects of toxic substances. Principles of work safety with toxins and poisonous organisms.
The ability of orientation in the basic toxicology with an overview of the main groups of microbial, plant, fungal and animal toxins, biochemical mechanisms of effects of toxic substances. Principles of work safety with toxins and poisonous organisms.
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Prerequisites
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Basic knowledge of plant physiology, animal physiology and taxonomy of presented groups.
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Assessment methods and criteria
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Combined exam, Seminar work
Knowledge of the basic toxicology with an overview of the main groups of microbial, plant, fungal and animal toxins, biochemical mechanisms of effects of toxic substances. Principles of work safety with toxins and poisonous organisms - plants and animals mainly invertebrates, amphibians, reptiles.
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Recommended literature
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Hayes, A.W., Kruger, C.L. Hayes' Principles and Methods of Toxicology. CRC Press New York, 2014. ISBN 9781842145364.
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Hrdina, V. a kol. Přírodní toxiny a jedy. Galén/Karolinum Praha, 2004. ISBN 80-7262-256-0.
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Ruckebusch, Y., Toutian, P.-L., Koritz, G.D. Veterinary pharmacology and toxicology. Springer Netherlands, 1983. ISBN 978-94-009-6604-8.
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Vorel, F. Toxikologie. JU České Budějovice, 1996.
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