Lectures: 1. Introduction to biophysics, physical description of biological systems, bioenergetics, energy transfer and conversion in a living organism, thermodynamic principles, the concept of entropy, heat, temperature, thermal comfort of an organism. 2. Storage and transmission of information in living systems, regulatory systems. 3. Properties of dispersion systems, diffusion, osmosis and its physiological significance, cryoscopy, ebullioscopy. 4. Structure and function of biologically important molecules: water, nucleic acids, proteins. 5. Cell as a biophysical system - structure, transport mechanisms, membrane potentials, mechanical properties. 6. Biophysics of tissues and organs (biophysics of blood circulation, respiration, locomotor system, bones and joints, muscles, cardiovascular system, respiration, excretory system, digestive system, electrical and magnetic properties of tissues. 7. Biophysics of information reception and processing (perception of chemical stimuli, acoustic signals, light stimuli). 8. Biophysics of electrical manifestations and effects (electric current, effects of electric current on the organism, electromagnetic field). 9. Biophysical bases of non-invasive treatment methods (treatment methods using mechanical energy, treatment methods using electric current, principles of treatment with magnetic fields, treatment methods using heat, treatment methods using light, physical principles of treatment with ionizing radiation). 10. Biophysical principles of invasive treatment methods (physical principles of modern surgical instruments, physical principles of main dental instruments, devices supporting or replacing organ function). Training: 1. Bioenergetics, energy transfer and conversion in a living organism, thermodynamic principles, the concept of entropy, heat, temperature, properties of disperse systems, diffusion, osmosis. 2. Structure and function of biologically important molecules: water, nucleic acids, proteins. 3. Cell as a biophysical system - structure, transport mechanisms, membrane potentials, mechanical properties. 4. Biophysics of tissues and organs (biophysics of blood circulation, respiration, locomotor system, bones and joints, muscles, cardiovascular system, respiration, excretory system, digestive system, electrical and magnetic properties of tissues. 5. Biophysics of electrical manifestations and effects (electric current, effects of electric current on the organism, electromagnetic field), diagnostic and therapeutic methods.
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The course introduces the basics of biophysics and its use in medical diagnostic and therapeutic methods. It provides basic information about the physical differences of individual methods and their biological effects. Students are acquainted with various types of these methods and devices used for examinations. Seminars complement and provide practice of the curriculum in the lectures.
The student: - explains terms (bioenergetics, entropy, heat, temperature, thermal comfort of the organism) - physically describes biological systems, energy transfer, and conversion in a living organism, thermodynamic principles - describes the storage and transmission of information in live systems - defines the structure and function of water molecules, nucleic acids, proteins - defines the cell - is familiar with the biophysics of tissues and organs - describes the biophysics of information reception and processing and electrical manifestations - is familiar with the biophysical basis of non-invasive and invasive treatment methods
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BENEŠ, J. Základy lékařské biofyziky. Praha: Karolinum, 2007. ISBN 978-80-246-1386-4.
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Hálek, J. Biofyzika pro bakaláře. Olomouc: Univerzita Palackého, 2003. ISBN 80-244-0529-6.
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Hrazdira, I., Mornstein, V. Lékařská biofyzika a přístrojová technika. Brno, 2001. ISBN 80-902896-1-4.
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MORNSTEIN, V., ŠKORPÍKOVÁ, J. Základy biofyziky a zdravotnické techniky. Neptun, 2006.
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NAVRÁTIL, L., ROSINA, J. Biofyzika v medicíně. Praha: Manus, 2003. ISBN 80-86571-03-3.
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Navrátil, L., Rosina, J. Medicínská biofyzika. Grada, Praha, 2005. ISBN 80-247-1152-4.
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ROSINA, J., VRÁNOVÁ, J., KOLÁŘOVÁ, H., STANĚK, J. Biofyzika pro zdravotnické a biomedicínské obory.. Praha: Grada, 2013. ISBN 978-80-247-4237-3.
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