Course: Biophysics

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Course title Biophysics
Course code ULZ/EDBIF
Organizational form of instruction Lecture + Lesson
Level of course unspecified
Year of study not specified
Semester Summer
Number of ECTS credits 3
Language of instruction English
Status of course unspecified
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Course availability The course is available to visiting students
Lecturer(s)
  • Šíp Miroslav, doc. RNDr. DrSc.
Course content
Lectures: 1. Introduction to biophysics, physical description of biological systems 2. Transmission and transformation of energy in the living organism, thermodynamic principles, concept of entropy, heat, temperature, thermal comfort of the organism 3. Preservation and transmission of information in living systems, control systems 4. Properties of dispersion systems, osmosis and its physiological significance, cryoscopy, ebulioscopy 5. Structure and function of biologically important molecules: water, nucleic acids, proteins. 6. Cell as biophysical system 7. Biophysics of tissues and organs (bones and joints, muscles, cardiovascular system, breathing, excretory system, digestive system, electrical and magnetic properties of tissues) 8. Biophysics of information reception and processing (perception of chemical stimuli, acoustic signals, light stimuli) 9. Biophysics of external factors (effects of mechanical factors, acoustic factors, influence of meteorological conditions on the organism, effects of electric currents, effects of magnetic fields, effects of non-ionizing electromagnetic radiation, biological effects of ionizing radiation) 10. Biomechanics (blood circulation, respiration, locomotive system, effects of mechanical forces on the organism) 11. Biological signals, biophysics of electrical expressions and effects (electric current, transport mechanisms, membrane potentials, effects of electric current on the organism, electromagnetic field, electrical physicochemical methods) 12. Optics and biophysics of vision (properties of radiation, sources and radiation detectors), acoustics, ultrasound, X-rays 13. Biophysical basics of noninvasive therapeutic methods (mechanical methods of healing, medical methods using electric current, principles of magnetic field treatment, heat treatment methods, therapeutic methods using light, physical principles of treatment with ionizing radiation) 14. Biophysical principles of invasive treatment methods (physical principles of modern surgical instruments, physical principles of major dental instruments, devices supporting or replacing organ function) Seminars: Seminars complement and practice the substance discussed in the lectures. During the semester the students prepare a seminar paper on the given topic and selected papers are presented by the students at the seminars. Seminars 1. Bioenergetics, energy transmission and transformation in the living organism, thermodynamic principles, concept of entropy, heat, temperature, properties of dispersion systems, diffusion, osmosis. 2. Structure and function of biologically important molecules: water, nucleic acids, proteins. 3. Cell as biophysical system structure, transport mechanisms, membrane potentials, mechanical properties. 4. Biophysics of tissues and organs (biophysics of blood circulation, respiration, musculoskeletal system, bones and joints, muscles, cardiovascular system, respiration, excretory system, digestive system, electrical and magnetic properties of tissues. 5. Biophysics of electrical expressions and effects (electric current, effects of electric current on the organism, electromagnetic field), diagnostic and therapeutic methods.

Learning activities and teaching methods
Monologic (reading, lecture, briefing)
Learning outcomes

Mastering the basics of biophysics and its applications in medicine Knowledge of physical principles of selected diagnostic and therapeutic methods An overview of the influence of physical factors on the body
Prerequisites
unspecified

Assessment methods and criteria
Combined exam

Mastering the substance within the scope of the syllabus Active participation in seminars and seminar work.
Recommended literature
  • Beneš. Základy lékařské biofyziky.
  • Hrazdíra. Lékařská biofyzika a přístrojová technika.
  • Rosina. Biofyzika pro studenty zdravotnických oborů.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester