| Course title | Courses of work with molecular data in R | 
|---|---|
| Course code | KBO/148 | 
| Organizational form of instruction | Lesson | 
| Level of course | Doctoral | 
| Year of study | not specified | 
| Frequency of the course | In academic years starting with an even year (e.g. 2024/2025), in the winter semester. | 
| Semester | Winter | 
| Number of ECTS credits | 4 | 
| Language of instruction | English | 
| Status of course | Compulsory-optional | 
| Form of instruction | Face-to-face | 
| Work placements | This is not an internship | 
| Recommended optional programme components | None | 
| Course availability | The course is available to visiting students | 
| Lecturer(s) | 
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| 
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| Course content | 
| Content of practicals: Basic methods of work R programming language, theory of methods used (there are short lectures before every practical session) Basic work in R - how to enter commands, install packages, read help, types of variables, indexes, etc.; Bioconductor; Load and export molecular data of various types and formats; Download molecular data from on-line databases; Extractions of SNP from sequencing data; Extraction of polymorphism from sequences; Mikrosatellites, AFLP, SNP, sequences, ?; Manipulations with data, conversions among formats; Distance matrices, import of custom matrices; Export of data; Basic statistics; PCoA; Phylogenetic trees (NJ, UPGMA, ML) and display and test; MSN; Basic statistics, genetic indices heterozygosity, HWE, F-statistics; DAPC; Whole genome SNP data; Spatial analysis - Mantel test, Moran's I, Monmonier, sPCA, ?; Basic map creation; Structure; Alignments; Manipulations with trees, work with big sets of trees; Phylogenetic independent contrast; Phylogenetic autocorrelation; Phylogenetic PCA; Ancestral state reconstruction; Additional extending topics? | 
| Learning activities and teaching methods | 
| Activating (simulations, games, drama) 
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| Learning outcomes | 
| To teach students analysis of molecular data in R programming language, introduce packages available for analysis of molecular data. Practical work, analyzing of own or provided data. | 
| Prerequisites | 
| unspecified | 
| Assessment methods and criteria | 
| Interim evaluation | 
| Recommended literature | 
| 
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| Study plans that include the course | 
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | 
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