Course: Organic Chemistry

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Course title Organic Chemistry
Course code KCH/DOCHE
Organizational form of instruction Lecture + Lesson
Level of course Bachelor
Year of study not specified
Semester Summer
Number of ECTS credits 3
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Kubec Roman, doc. Ing. Ph.D.
Course content
1. History, fundamental principles and terminology of organic chemistry. Representation of organic compounds using models, formulas and names. Intermolecular interactions and their effect on physical properties of compounds. 2. Constitutional and configuration isomerism. Chirality. Physical, chemical and biological properties of isomers, R/S configuration, diastereomers and enantiomers, meso-compounds, homologues and analogues. 3. Most important types of organic compounds, basic IUPAC nomenclature. 4. Alkanes and cycloalkanes. Nomenclature, physical and biological properties, conformation of alkanes, Newman projection. Radicals and carbocations, most important reactions of alkanes. 5. Alkenes and alkynes. Nomenclature, physical and biological properties. Structure of double bond and triple bond, geometric isomerism, determination of cis/trans resp. Z/E configuration. Most important reactions. 6. Arenes. Conjugation, delocalisation and aromaticity. Benzene and its derivatives, physical and biological properties. Reactions of aromatic substances. Most important condensed aromatic hydrocarbons. 7. Halogenalkanes. Nomenclature of halogen-based compounds. Physical and biological properties of halogen derivatives. Most important reactions. Freons, Teflon, persistent halogenated compounds. 8. Alcohols, ethers, epoxides and phenols. Nomenclature of hydroxy-compounds and ethers. Physical and biological properties. Acid-base properties of alcohols and phenols. Most important reactions of alcohols. 9. Carbonyl compounds. Aldehydes, cetones and quinones, fundamentals of carbonyl compounds nomenclature, their physical and biological properties. Most important reactions. 10. Carboxylic acids and their derivatives. Physical and biological properties, most important reactions. Derivatives functional and substitutive. Acid-base properties of carboxylic acids derivatives. 11. Most important organic compounds of nitrogen. Amines and imines, structure, physical and biological properties, most important reactions. Nitro- and nitroso- compounds. Heterocyclic compounds and alkaloids. 12. Saccharides. Fundamental classification, linear and cyclic forms of saccharides, stereoisomerism of saccharides, Fisher's, Haworth's and Tollens's formulas. Most important saccharides. 13. Amino-acids, peptides and proteins. Fundamental classification, coded amino-acids, essential and non-essential amino-acids. Stereoisomerism of amino-acids, Fischer's formulas. Isoelectric point. Most important reactions of amino-acids. Peptide bond. 14. Fatty acids, lipids, waxes. Fundamental classification, physical and biological properties. Most important reactions of lipids. Other lipophilic compounds (sterols, lipophilic vitamins). Laboratory exercises (proceed within the scope of 3 hours per week) 1. Laboratory code of practice. Fundamental techniques used in organic chemistry laboratory. 2. Preparation of N-acetanilide. 3. Preparation of ethyl-formate. 4. Control of the purity of products: a) N-acetanilide by determination of its melting point. b) ethyl-formate using refractometer and pycnometer. 5. Separation of color compounds using column and thin-layer chromatography. 6. Important reactions of saccharides and proteins.

Learning activities and teaching methods
Monologic (reading, lecture, briefing), Laboratory
  • Class attendance - 40 hours per semester
  • Preparation for exam - 18 hours per semester
  • Preparation for credit - 10 hours per semester
Learning outcomes
The course is aimed to provide theoretical fundamentals of organic chemistry, to explain basic principles of nomenclature of organic compounds, and to cover main classes of organic compounds with the emphasis on their physical, biological and chemical properties. During laboratory exercises, students are expected to gain basic laboratory skills used in organic chemistry.
After successful passing the course, students are expected to be familiar with main classes of organic compounds, their nomenclature and physical, biological and chemical properties. The acquired knowledge may be employed in other chemistry disciplines and related fields (both in research and commercial laboratories).
Prerequisites
Conditional subjects: KLZ/DOFCH KLZ/DORCH
KCH/DORCH

Assessment methods and criteria
Combined exam

To successfully pass the course, the student has to: 1) complete the laboratory exercises, 2) achieve at least 51% of a written test.
Recommended literature
  • Fikr, J. a Kahovec, J. Názvosloví organické chemie. Rubico, Olomouc, 2008.
  • Kubec, R. a Dadáková, E. Laboratoř organické chemie. ZF JU, České Budějovice, 2017.
  • Kubec, R. Úlohy z organické chemie. ZF JU, České Budějovice, 2017.
  • McMurry, J. Organická chemie. Vutium, Brno, 2015.
  • Pacák, J. Jak porozumět organické chemii. Karolinum, Praha, 2007.
  • Pacák, J. Reakce organických sloučenin. Karolinum, Praha, 2007.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Health and Social Sciences Study plan (Version): Health Technician (2) Category: Health service 1 Recommended year of study:1, Recommended semester: Summer