Course: Molecular Biology of the Cell

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Course title Molecular Biology of the Cell
Course code KGZB/MBGB
Organizational form of instruction Lecture + Lesson
Level of course Master
Year of study 2
Semester Winter
Number of ECTS credits 6
Language of instruction Czech
Status of course Compulsory
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
  • Čurn Vladislav, prof. Ing. Ph.D.
  • Beran Pavel, Ing. Ph.D.
  • Stehlíková Dagmar, Ing. Ph.D.
Course content
1. Structure and ultrastructure of prokaryotic and eukaryotic cells, structure of prokaryotic and eukaryotic genes and genome. Genomic characteristics of viruses and viroids. Cell cycle, molecular cell view and cellular processes. 2. Chemical composition of the cell, structure and function of biomolecules, functional classification of biomolecules. Biomembranes, organelles. 3. Structure and function of proteins, membrane proteins, protein purification and detection. 4. Nucleic acids, structure, function. 5. Basic molecular genetic mechanisms in prokaryotes and eukaryotes. Replication, repair. 6. Transcription and post-transcriptional adaptations. 7. Translation and post-translational adaptations. 8. Regulatory mechanisms, regulatory genes and their products, positive and negative regulation, activation and repression. 9. Regulation on post-transcriptional, translation, post-translational, regulation. 10. Molecular structure of genes and chromosomes. Genomic stability, polyploidization, duplication and modification of genes at the genomic and genomic level.

Learning activities and teaching methods
Monologic (reading, lecture, briefing)
  • Preparation for credit - 35 hours per semester
  • Preparation for exam - 45 hours per semester
  • Semestral paper - 45 hours per semester
  • Class attendance - 56 hours per semester
Learning outcomes
The aim of the course is to acquire knowledge about structure and function of prokaryote and eukaryote genomes and basic molecular processes at cell level
Students are able to orientate in the field of cell and molecular biology
Standard knowledge of biology

Assessment methods and criteria
Oral examination

Active participation in exercises, protocols from laboratory exercises, understanding the curriculum defined for the exam.
Recommended literature
  • Čurn V., Sáková L.:. Molekulární biologie. ZF JU 1998, 130 s..
  • Lodish, H. a kol. Molecular Cell Biology, Macmillan Higher Education, 2016, 1280 s..
  • Rosypal, S. . Úvod do molekulární biologie I-IV. 4. inovované vydání, Brno, 2006. 290 s.
  • Rosypal, S. Úvod do molekulární biologie I-IV. 3. rozšířené vydání, Brno, náklad vlastní 2002. 320 s..
  • studijní materiály.

Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Agriculture Study plan (Version): Agricultural Biotechnology (2017) Category: Agriculture and forestry 2 Recommended year of study:2, Recommended semester: Winter