Course: Molecular Phylogenetics

« Back
Course title Molecular Phylogenetics
Course code KGZB/MFL
Organizational form of instruction no contact
Level of course Doctoral
Year of study not specified
Semester Winter and summer
Number of ECTS credits 0
Language of instruction Czech
Status of course Compulsory-optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Hypša Václav, prof. RNDr. CSc.
  • Čurn Vladislav, prof. Ing. Ph.D.
Course content
Thematic blocks of lectures: Specifics of molecular biological data, their advantages and disadvantages. Acquisition of molecular biological data for the purposes of systematics (sequencing, RFLP, RAPD, AFLP, allozymes, microsatellites, SSCP, reassociation analysis, immunological methods, protein fingerprinting). Processing of acquired data - phenetic and cladistic approaches, distance and character data, methods of distance calculation based on different types of character data, construction of dendrograms, UPGMA, NJ, ML, ME, comparison of two dendrograms, reliability testing of individual branches of dendrograms (jackknifing, OUT-jakknifing , bootstrapping). Biological interpretation of results. Software for molecular phylogenetics.

Learning activities and teaching methods
Monologic (reading, lecture, briefing)
  • Semestral paper - 90 hours per semester
  • Preparation for classes - 50 hours per semester
  • Preparation for exam - 50 hours per semester
  • Class attendance - 56 hours per semester
Learning outcomes
The aim of the course is mastering of the methods and techniques of molecular phylogenetics, with the aim to use molecular biological data in the systematics and related biological fields.
The student can independently navigate in the given issue and is able to use the acquired knowledge in their scientific activities or other practice.
Prerequisites
The student is familiar with the issues within the scope of university studies and is willing to study independently.

Assessment methods and criteria
Oral examination

Standard knowledge of genetics and statistics
Recommended literature
  • Avise, J. C. Molecular Markers, Natural History and Evolution. New York, Chapman & Hall 1993, 684 s..
  • Graur, D., Li, W. H. Fundamentals of Molecular Evolution. Massachusetts, Sunderland Massachusetts 1999, 481 s..
  • Hillis, D. M., Moritz, C., Mable, B. K. Molecular Systematics. Sinauer Assocites, Inc., Massachusetts, Sunderland Massachusetts 1996, 655 s..
  • Li, W. H. Molecular Evolution. Sinauer Assocites, Inc., Massachusetts, Sunderland Massachusetts 1997, 487 s..


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Agriculture Study plan (Version): Agricultural Biotechnology (1) Category: Agriculture and forestry - Recommended year of study:-, Recommended semester: -
Faculty: Faculty of Agriculture Study plan (Version): Agricultural Biotechnology (1) Category: Agriculture and forestry - Recommended year of study:-, Recommended semester: -