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Lecturer(s)
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Zdráhal Zbyněk, doc. Ing. Dr.
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Čurn Vladislav, prof. Ing. Ph.D.
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Course content
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Functional proteins. Mutagenesis as a source of variability and functional activity of proteins. Proteomic methods for variability identification. Genetic determination of antibody production and immunological adaptation. Subgenes and their rearrangement. Antigens and haptens. Methods of immunogenetic analysis. The importance of functional activity of genes for the creation of active health and the production of safe food of animal origin.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing)
- Semestral paper
- 90 hours per semester
- Preparation for classes
- 50 hours per semester
- Class attendance
- 56 hours per semester
- Preparation for exam
- 50 hours per semester
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Learning outcomes
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The aim of the course is mastering knowledge about the genetic determination of polymorphism of functional proteins and immune responses in animals and also to apply and develop proteomic and immunogenetic methods.
The student can independently navigate in the given issue and is able to use the acquired knowledge in their scientific activities or other practice.
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Prerequisites
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The student is familiar with the issues within the scope of university studies and is willing to study independently.
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Assessment methods and criteria
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Oral examination
Standard knowledge of genetics, physiology and biochemistry
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Recommended literature
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Brown, T. A. Genomes. 2nd e. London, Taylor & Francis 2002, 624 s..
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Griffits, A. J. F. Modern genetic analysis. New York, W. H. Freeman 1999, 449 s..
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Rosypal, S. Úvod do molekulární biologie I. - V. Brno, Rosypal 2002, 1 200 s..
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Sršeň, Š., Sršňová, K. Základy klinickej genetiky a jej molekulárna podstata. Bratislava, Osveta 2000, 409 s..
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Watson, J. D. Molekulární biologie genu. Praha, Academia 1997, 757 s.
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