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Lecturer(s)
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Čítek Jindřich, prof. Ing. CSc.
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Course content
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Nucleic acids, their components, nucleozids, nucleotids, chemical structure. DNA and RNA, structure, superhelix, biosynthesis, promotors, terminators. Replication, ORI, Okazaki fragments, DNA polymerases. Transcription unit, transcription, RNA polymerases, posttranscriptional changes. Genetic code. Translation, iniciation, termination. Supresors, ORF. Regulation positive, negative, activation, repression. Regulation posttranscriptional, translational, posttranslantional.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing)
- Preparation for credit
- 50 hours per semester
- Preparation for exam
- 90 hours per semester
- Semestral paper
- 40 hours per semester
- Class attendance
- 20 hours per semester
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Learning outcomes
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Knowledge of biopolymers, structure, function. Expression, gene regulation. Mutation, transposition.
Basis of molecular biology for subsequent study of gene engineering, biotechnologies etc.
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Prerequisites
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genetics - GEN or genetics - GENZO
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Assessment methods and criteria
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Combined exam
Attending of teaching. Credit test.
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Recommended literature
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Darnell, J. a kol. Molecular Cell Biology. Sci. Am. Books, 930 s., 1990.
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Lewin, B. Genes VI. Univ. Press, 990 s., 1997.
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Rosypal, S. Úvod do molekulární biologie I-III. Brno, náklad vlastní, 620 s., 1997.
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