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Lecturer(s)
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Hashimi Hassan, doc. Mgr. Ph.D.
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Hampl Aleš, doc. MVDr. CSc.
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Žurovec Michal, prof. RNDr. CSc.
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Anděra Ladislav, RNDr. CSc.
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Sobotka Roman, prof. Ing. Ph.D.
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Doležel David, Mgr. Ph.D.
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Lazar Josef, Mgr. Ph.D.
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Doležal Tomáš, doc. Mgr. Ph.D.
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Bruce Alena, RNDr. Ph.D.
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Valdés James Jason, Ph.D.
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Benz Corrina, Mgr. Ph.D.
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Course content
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Lectures: 1. Michal Žurovec: G-protein signaling and associated pharmacology 2. Michal Žurovec: Growth, insulin signaling and metabolic regulations 3. Alena Krejčí: Notch, hedgehog and Wnt signalling 4. Alena Krejčí: Receptor kinases, nuclear receptors and noise in signalling. 5. Roman Sobotka:The making of a chloroplast; light signalling in photomorphogenesis 6. Tomaš Doležal: Molecular regulation of immune response - innate immunity, Drosophila model and evolutionary view 7. Ryan Rego: Subversion of Cell Signalling by Pathogens. 8. Ladislav Andera: Molecular mechanisms of Regulated Cell Death 9. Aleš Hampl: Embyonic stem cells - biology, promises and drawbacks 10. James Valdes: Molecules & behaviour 11. Josef Lazar: Molecular mechanisms in neuronal signaling - ion channels, neurotransmitters, neural circuits 12. David Doležel: Circadian rhythms 13. Hassan Hashimi: Mitochondria throughout eukaryotes: their diversity and conservation of form and function 14. Journal Club sessions after lecture series. Number depends on number of students enrolled.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing), Dialogic (discussion, interview, brainstorming)
- Preparation for classes
- 40 hours per semester
- Class attendance
- 28 hours per semester
- Preparation for exam
- 40 hours per semester
- Preparation for credit
- 40 hours per semester
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Learning outcomes
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This course covers topics cell signaling and regulation such as apoptosis, Wnt-signaling, G-coupled receptors, nuclear receptors, innate immunity and organelle function.
Students will learn to be more conversant in Scientific English becuase the lectures are given in this language by experts on a given subject. Students are encouraged to actively participate in lectures for this aim. Students will also learn who to read scientific literature and present scientific data in English thanks to the Journal Club component of the course.
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Prerequisites
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Ability to communicate in English (Active and Passive). A basic molecular and cell biology from your home institution. For students of PrF JCU this is Molecular Biology (KMB/250). For Bioloical Chemistry Students of JCU and JKU it is Molecular Biology and Genetics (KMB/758)
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Assessment methods and criteria
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Student performance assessment, Analysis of student's work activities (technical works), Test
Due to the number of students enrolled in the course, the journal club will be given as at least two separate sessions in which a scientific paper will be presented by a group of students. The time and place of the journal clubs will be determined later among the students. Journal club attendance is mandatory for all students taking the course for credit to take the final exam (zápočet). Extra points toward the final exam will be given in the journal club based on performance and lecture attendance. Participation in ALL Journal Club sessions and group presentation of one scientific article from a list compiled from those recommended by lecturers Exam: To pass, students must get 70%. Extra points are earned accroding to Journal Club performance (qualtity of presentation, active participation in discussion, performanceon quizzes testing if papers were read by students).
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Recommended literature
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selected research papers for each topic.
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Alberts et al. Molecular Biology of the Cell, 6th ed.. 2014. ISBN 9780815344322.
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