UNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Study programmes & Course catalogue
for academic year 2026/2027
UNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
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Course: Immunology

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Course title Immunology
Course code KME/723
Organizational form of instruction Lecture
Level of course Master
Year of study 2
Frequency of the course In each academic year, in the summer semester.
Semester Summer
Number of ECTS credits 3
Language of instruction English
Status of course Compulsory-optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Course availability The course is available to visiting students
Lecturer(s)
  • Chmelař Jindřich, doc. RNDr. Ph.D.
Course content
1. Immunity ? overview of the basic functions: the role of immune system, innate and adaptive immunity, regulation of the immune system. 2. Experimental systems in immunology. Cells and organs of the immune system: lymphocytes, mononuclear phagocytes, granulocytes, primary and secondary lymphoid organs, recirculation of lymphoid cells. 3. Antigens: chemical and biological properties, adjuvants, haptens, viral and bacterial antigens, mitogens,. Structure and function of immunoglobulins: antigenic determinants, on immunoglobulins, properties and function of immunoglobulin classes. 4. Antigen - antibody interaction: affinity avidity, immunological cross-reactivity. Immunochemical reaction. Monoclonal antibodies. 5. Organisation and expression of immunoglobulin genes.: development of antibody diversity. 6. Major histocompatibility complex: structure and function of MHC molecules. T-receptor: development of TCR diversity, MHC restriction, development of T cells. 7. Cytokines: structure and function of cytokines and their receptors. Development of humoral immune response: primary and secondary response, antigen presentation, role of cytokines,. 8. Cell-mediated immunity: T-cell cytotoxicity, antibody-dependent cell-mediated cytotoxicity, delayed type of hypersensitivity. Regulation of immunity, immunological tolerance. 9. The complement system: classical pathway, alternative and lectin pathway of complement activation, regulation. Hypersensitivity: immediate and delayed hypersensitivity, anaphylaxis, hypersensitivity from immune complexes. 10. Vaccines: inactivated, attenuated, subunit, recombinant, vector vaccines. Immune response to infection: viral, bacterial and parasitic infections. 11. Transplantation immunology: transplantation antigens, mechanisms of graft rejection, immunosuppression. Anti-cancer immunity: malignant transformation of cells, tumour antigens, tumour immunotherapy.

Learning activities and teaching methods
Monologic (reading, lecture, briefing)
  • Class attendance - 28 hours per semester
  • Preparation for exam - 40 hours per semester
  • Preparation for classes - 28 hours per semester
Learning outcomes
Students are introduced to the structure and function of immune system, natural and adaptive immunity and its regulation.
Students will gain the basic knowledge about the structure and function of immune system.
Prerequisites
Not specified

Assessment methods and criteria
Oral examination

Knowledge from the lectures is assessed by a written test consisting of multiple-choice questions (4 options, one correct answer), completion of terms in a text, and open-ended questions. The student must achieve at least 50% correct answers.
Recommended literature
  • Coico R., Sunshine G.: Imunology: a short course (6th ed.), John Wiley & Sons, Inc., Hobojem, New Persey 2009, 391.
  • Kindt TJ., Goldsby R.A., Osborne B.A.: Kuby Immunology (6th ed.), W.H. Freeman and Copany, New York 2007, 574.
  • B M Hannigan. Immunology. SCION PUBLISHING, 2009. ISBN 1904842569.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
UNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE, date of update: 09.06.2026 23:50. Data created for academic year 2026/2027