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Lecturer(s)
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Fojtíková Pavla, Ing. Ph.D.
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Course content
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Introduction to Toxicology. How toxic substances work? Toxicokinetics, toxicodynamics, biotransformation. Exposure, monitoring, biological monitoring. Risk evaluation and prediction of toxicity. Risk assessment. Organ toxicity. Neurotoxicity, mutagenicity, carcinogenicity. Information sources in Toxicology. Safe Handling of Chemicals. Combat substances. Accidents in chemical industry.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing), Dialogic (discussion, interview, brainstorming), Work with multi-media resources (texts, internet, IT technologies)
- Class attendance
- 26 hours per semester
- Preparation for classes
- 5 hours per semester
- Preparation for exam
- 20 hours per semester
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Learning outcomes
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- to provide a basic and comprehensive overview of the importance of toxicology in both industry and daily life - to understand principles of harmful substances interaction with living organisms - to work with information sources in Toxicology
Students will gain a basic and comprehensive overview of the importance of toxicology in industry and in everyday life. Attention is paid to the interaction of harmful substances with living organisms. Individual study of scientific publications in the field of toxicology, presentation of knowledge. Individual work with information sources in Toxicology.
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Prerequisites
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The subject assumes knowledge of chemistry at the level of secondary school. Computer skills, basic knowledge of English.
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Assessment methods and criteria
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Combined exam, Interim evaluation
Searching and processing toxicological data. Oral exam.
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Recommended literature
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Horák J.,Linhart I.,Klusoň P.: Úvod do toxikologie a ekologie pro chemiky, VŠCHT Praha 2010..
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Linhart I.: Toxikologie interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky, VŠCHT Praha 2012.
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Paleček J., Linhart I., Horák J.: Toxikologie a bezpečnost práce v chemii, VŠCHT Praha 1999.
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PATOČKA, J. A kol.:. Vojenská toxikologie. Praha, Grada, 2004.
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PATOČKA, J.:. Úvod do obecné toxikologie. Praha, Manus, 2003.
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PROKEŠ, J. A kol.:. Základy toxikologie. Praha, Galén, 2005.
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Linhart I. Základní pojmy v toxikologii, ekologii a ekotoxikologii. Basic Terms in Toxicology, Ecology and Ecotoxicology.. Praha, 2019. ISBN 978-80-7592-040-9.
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