| Course title | Plasma in biomedicine and nanotechnology |
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| Course code | UFY/PBN |
| Organizational form of instruction | Lecture + Lesson |
| Level of course | Doctoral |
| Year of study | not specified |
| Frequency of the course | In each academic year, in the winter semester. |
| Semester | Winter |
| Number of ECTS credits | 5 |
| Language of instruction | Czech, English |
| Status of course | Compulsory-optional |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Course availability | The course is available to visiting students |
| Lecturer(s) |
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| Course content |
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Lecture 1. Nanotechnology - hot topics in the field (motivation and overview) Nanotechnology and their applications, Basic stones of nanotechnologies, Nanoparticles: morphology, preparation (top down, bottom up), shape and crystallization - Wulff theorem, Nanostructures, Plasma nanoscience - Low-temperature plasma as versatile nanotool, Fundamentals of plasma, Plasma technology Lecture 2. Advanced plasma diagnostics, in-situ and in-time monitoring of plasma processes for tailored nanotechnology Introduction, Probe diagnostic, Optical emission spectroscopy, Advanced optical methods, Corpuscular methods - mass spectrometry, Methods for plasma investigation, Time-resolved measurements Lecture 3. Optimization and tailoring of (plasma fabricated) nanostructures Parameters of the deposition process, (in-situ and in-time) monitoring / plasma diagnostics, Thin film analyses - survey, Surface Preparation for Films and Coatings - Cleaning, Physical vapour deposition (PVD) - cathode sputtering, Plasma Enhanced Chemical Vapour Deposition (PECVD), In-time and In-situ optimization of the deposition process Lecture 4. Growth of gas aggregated nanoparticles and GLAD films Introduction - dimensions of surfaces, Growth of gas aggregated nanoparticles, Haberland concept, Theory of the growth and formation of nanoparticles in GAS, Investigation of deposited clusters, size and size distribution, Multicomponent, multimaterial and core-shell nanoparticles, Advanced and alternative methods for production of nanoparticles, Glancing angle deposition - GLAD, Atomic layer deposition - ALD Lecture 5. Theory of thin film growth, nanocomposite coatings and films with plasma polymer matrix Thin film nucleation, growth, and microstructural evolution, Film formation and structure, Nanocomposite coatings for severe applications, Metal based nanocomposites and their properties, Plasma polymer composites Lecture 6. Plasma polymer films, chemical vapor deposition and plasma enhanced chemical vapor deposition Chemical vapor deposition, Plasma enhanced chemical vapor deposition, Plasma polymerization process, Metal based nanocomposites and their properties, Plasma polymer composites Lecture 7. Surface functionalization based on plasma techniques, surface treatment, surface free energy, cell-surface interaction, plasma-assisted tissue engineering and plasma etching Plasma polymer-surface treatment, Interaction of plasma with polymer surface, Plasma assisted modification of biointerfaces, Surface-free energy - hydrophobic and hydrophilic surfaces, Plasma etching Lecture 8. Antimicrobial surfaces Introduction - antimicrobial surfaces, Basic concept of antimicrobial coatings, Antibacterial non-fouling surfaces, Metal-based antimicrobials, Artificial Antibacterial Surfaces, doped and enriched thin films, Antibacterial surfaces for implants Lecture 9. Plasma for medicine: plasma sources, characteristics and plasma interaction with living tissue Introductory to biology and medicine, Discharges and their applicability for plasma medicine, Mechanisms of plasma interactions with cells, Plasma-assisted healing and treatment of diseases Lecture 10. Plasma sterilisation and decontamination Plasma Sterilisation of different surfaces, Plasma species and factors active for sterilisation, Physical and biochemical effects of plasma on microorganism, living tissue sterilisation, Plasma decontamination of air streams, Plasma decontamination of water, Plasma treatment of blood Lecture 11. Nanostructures for biosensors Introduction to nanomaterials for sensing applications, Biosensors and detection of complex systems, Biosensors based on surface plasmon effects, Surface enhanced Raman Spectroscopy, Fiber Optic Sensors - namely lossy mode resonance Lecture 12. Advances in (nano)material science, thin films and interfaces Functional Thin
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| Learning activities and teaching methods |
Monologic (reading, lecture, briefing), Laboratory, Practical training
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| Learning outcomes |
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The course focuses on modern trends in research and development in the area of plasma medicine and plasma nanotechnology. Main attention is devoted to nanostructured surfaces, prepared by low-temperature plasma, suitable for medical application. The direct interaction of plasma with living tissue are included, too.
Students will get an overview and basic knowledge of plasma medicine and plasma nanotechnologies, especially of nanostructured surfaces prepared by low-temperature plasma. These surfaces represnt a hot-topic and are widely applicable in biomedicine. Furthermore, the student will gain basic knowledge of plasma interaction with living organism. |
| Prerequisites |
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the knowledge of fields: electricity and magnetism, plasma physics, plasma technology, general physics
UFY/FP ----- or ----- UFY/FPE |
| Assessment methods and criteria |
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Oral examination, Test
Understanding of the topic within the frame given by the plan. Assesment methods and criteria linked to learning outcomes: credit: attendance of seminars, min 75%, passing the test to min 60%. exam: passing the test min 75%, proof of knowledge at the oral exam min 75%. |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Science | Study plan (Version): Biophysics (1) | Category: Physics courses | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Biophysics (1) | Category: Physics courses | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Biophysics (1) | Category: Physics courses | - | Recommended year of study:-, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Biophysics (1) | Category: Physics courses | - | Recommended year of study:-, Recommended semester: Winter |