Course: Selected chapters of biophysics

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Course title Selected chapters of biophysics
Course code UFY/VKB
Organizational form of instruction Lecture
Level of course Bachelor
Year of study not specified
Frequency of the course In each academic year, in the summer semester.
Semester Summer
Number of ECTS credits 3
Language of instruction Czech
Status of course Compulsory, Compulsory-optional
Form of instruction unspecified
Work placements unspecified
Recommended optional programme components None
  • Durchan Milan, RNDr. CSc.
Course content
Content of lectures: Molecules in universe. The role of bioelements in structures of organisms. Moleclar organisation of biological systems. Physics of water in its biological importance. Experimental methods of study of hydrogen bonds. Gibbs energy in molecular biology, basics of therodynamics. Electrostatic interactions. Spectroscopy of dimers. Weak chemical bonds in biological molecules. Forces determining the structure of nucleic acids. Hydrophobic effect and solvatation. Ionic interaction and S-S bonds in proteins. Peptidic bond and polypeptide chain. Conformation of proteins. Ramaendran's diagrams, potential function, structure prediction. Conformation of nucleic acids, bases, sugars, angles. DNA -B, A and Z forms.

Learning activities and teaching methods
Monologic (reading, lecture, briefing), Work with text (with textbook, with book), Demonstration, Projection, Individual preparation for exam, Excursion
  • Field trip - 3 hours per semester
  • Preparation for classes - 5 hours per semester
  • Semestral paper - 2 hours per semester
  • Class attendance - 28 hours per semester
Learning outcomes
Explain role of conformations and molecular interactions for structure and function of biological molecules.
Students intensify their secondary school knowledge of physics and interdisciplinary fields (biochemistry, photobiology,...).
An introductory course in biophysics, which aim is to popularize the discipline.

Assessment methods and criteria
Oral examination, Seminar work

Student's own presentation on one of the proposed topics, discussion on this topic. Oral exam.
Recommended literature
  • Bruce Alberts: Základy buněčné biologie, Úvod do molekulární biologie buňky, Espero Publishing, Ústí nad Labem, 2001.
  • J.David Rawn: Biochemistry, Neil Patterson Publishers, Burlington, N. Carolina, 1989.
  • Pavel Hobza, Rudolf Zahradník: Mezimolekulové komplexy - Úloha van der Waalsových systému ve fyzikální chemii a v biodisciplinách, Academia, Praha 1988.
  • Zdeněk Vodrážka: Fyzikální chemie pro biologické vědy, Academia, Praha 1982.

Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Science Study plan (Version): Physics (1) Category: Physics courses - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Biophysics (1) Category: Physics courses 1 Recommended year of study:1, Recommended semester: Summer