Lecturer(s)
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Course content
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Lectures: 1. Importance of biorhythms in living nature, history of chronobiology and its directions of applications in biomedicine 2. Basic characteristics in the analysis of biorhythms, levels and manifestations of biorhythms, specifics in research and clinical applications 3. Biorhythm data processing in laboratory medicine. Genetic principles of biorhythm regulation 4. Biorhythms of proliferation 5. Time structure of the human organism 6. Biorhythm changes in ontogenesis 7. Physiological mechanisms of biorhythm synchronization regulation 8. Biorhythm change under extreme conditions 9. Chronopathology. Circadian rhythms in tumours. Chronopharmacology and chronotoxicology 10. Biorhythms in the haematoimmune system. Biorhythms and mental hygiene
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing)
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Learning outcomes
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The temporal structure of the human organism is important in the interpretation of the values of some laboratory characteristics.
After completing the course, students will understand the importance of some oscillations in physiological regulation and changes in the effects of chronobiotics. Students will also learn to integrate the time structure of the human body as an important factor in interpreting the values of some laboratory characteristics.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Student performance assessment, Interview, Systematic student observation
Oral presentation on a given topic
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Recommended literature
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Berger J. Biorytmy. Praha Paseka, 1995.
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DUNLAP J.C., LOROS J.J., DeCOURSEY P.P. Chronobiology - Biological Timekeeping. Sinauer Associates, Sunderland, Massachusetts, 2004. ISBN 0878933964.
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KLEIN G. Farewell to the Internal Clock. Springer, New York, 2007. ISBN 9780387403151.
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Touitou Y., Haus E. Biologic Rhythms in Clinical and Laboratory Medicine. Springer Berlin, 1994.
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