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Lecturer(s)
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Zemanová Eva, Ing. Ph.D., MBA
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Freitinger-Skalická Zuzana, PhDr. Ph.D.
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Kaňkovský Josef, Mgr.
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Course content
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Lectures (2 lessons): 1. Mechanism of action of ionizing radiation, radiation protection. 2. Radioactive substances. 3. Possibilities of entry of radioactive substances into the mammalian organism, their fate and distribution in the organism. 4. Ways of retaining and excreting radioactive substances in the mammalian organism. 5. Diagnostic possibilities of radionuclide contamination, their prophylaxis and treatment. 6. Risky activities that may lead to the contamination of persons with radioactive substances. 7. Ways and procedures to minimize contamination risks. 8. Evaluation of the severity of radiation damage to individual critical organ systems or organs after internal contamination and damage to the skin and mucous membranes after external contamination. 9. Biophysical units that are important in assessing the severity of radiation damage. 10. Relationships dose - effect of ionizing radiation, various examples. Seminars (1 lesson): 1. Use of RaL in healthcare. 2. Radiopharmaceuticals, radionuclides in healthcare with a focus on RaL contamination. 3. Radiation accidents and accidents with a focus on RaL contamination. 4. Combined radiation damage. 5. Iodine prophylaxis. 6. Decontamination. 7. Decontamination ? excursion at the FRS of the region. 8. Principles and possibilities of external contamination detection. 9. Principles and possibilities of internal contamination detection. 10. Principles and possibilities of detection of external and internal contamination RaL - SÚJB excursion.
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Learning activities and teaching methods
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unspecified
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Learning outcomes
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The aim of the subject is to clarify the mechanisms of contamination and interaction of radioactive substances with the mammalian organism, the distribution of these substances in organisms and the methods and evaluation of radiation damage to organs, and to provide an overview of the risks of contamination in healthcare and other activities in industry.
Competence acquired: The student will acquire theoretical knowledge about the mechanism of the effects of ionizing radiation and important chemical substances of a natural and synthetic nature. They will be able to assess the degree of damage caused by these noxes and suggest possible preventive measures. Students will be able to propose general and necessary safety measures when dealing with these noxes and participate in the solution of extraordinary events associated with their use or their release into the environment.
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Prerequisites
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unspecified
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Assessment methods and criteria
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unspecified
The condition for granting credit is a seminar work; the exam will take place in the form of a written test on the content of the lectures and seminars. Student requirements: Participation in seminars, seminar paper - power-point presentation.
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Recommended literature
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Feltl, D., Cvek, J. Klinická radiobiologie. Havlíčkův Brod, 2009. ISBN 9788073111038.
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FILIPOVÁ, A. a kol. Radiační ochrana při radiační mimořádné události.
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HAVRÁNKOVÁ, Renata, ed. Klinická radiobiologie.
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HAVRÁNKOVÁ, Renata, ed. Klinická radiobiologie.
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NAVRÁTIL, L., ROSINA. R. Medicínská biofyzika. 2.
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Österreicher, J., Vávrová, J. Přednášky z radiobiologie. Manus, Praha, 2003.
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OTŘÍSAL, Pavel a ZAHRADNÍČEK, Radim. Vyhodnocování radiační, chemické a biologické situace.
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Podzimek, František. Radiologická fyzika. Aplikace ionizujícího záření. 1. vydání, multimediální verze. [Praha] : České vysoké učení technické v Praze, 2021. ISBN 978-80-01-06829-8.
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