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Lecturer(s)
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Čítek Jindřich, prof. Ing. CSc.
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Večerek Libor, Ing. Ph.D.
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Course content
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1. Introduction to the study of genetics. Genetic processes at the molecular level. 2. Chemical basis of heredity, nucleic acids, their structure and function. Implementation of genetic information. 3. Eukaryotic and prokaryotic genome. Nucleotide sequences. Gene. Regulation of gene action. 4. Basic molecular genetic methods. Genetic polymorphism. Biological basis of genomic selection. 5. Basics of cytogenetics and karyology, principles and methods for determining karyotypes in animals and plants and their use. 6. Mendelian genetics. 7. Genetic linkage. Cytological and genetic regularities of linkage, construction of genetic maps. 8. Genome mapping. 9. Methods of genetic analysis of sex related genes. 10. Introduction to genetic interactions. 11. Mutations and mutagenesis - variability increase factor at the level of genes, non-coding sequences, chromosomes and genome, classification of mutagenes and mutations, suppression and repair of mutations. 12-14 Genome Analysis Methods.
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing)
- Preparation for credit
- 15 hours per semester
- Preparation for exam
- 25 hours per semester
- Semestral paper
- 25 hours per semester
- Class attendance
- 56 hours per semester
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Learning outcomes
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Completion of the course Genetics I provides a comprehensive set of basic genetic knowledge. It is therefore a suitable subject for all students regardless of the program studied. It is the initial level of genetic knowledge for the follow-up subject Genetics II and other applied disciplines of specialized fields of study.
Knowledge of molecular, cell, Mendelian genetics, immunogenetics, mutations. Fundamentals for the study of consequent genetic disciplines.
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Prerequisites
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Organic chemistry - KCH/OCHVZ, Biochemistry - KCH/BCHVZ
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Assessment methods and criteria
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Student performance assessment
Knowledge in genetics. Credit tests.
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Recommended literature
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Čítek, J. a kol. Cvičení z genetiky. ZF JU České Budějovice, 2011.
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Čítek, J. a kol. Vybrané návody k laboratorním cvičením z molekulární biologie. ZF JU České Budějovice, 2014.
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Gardner R.J. et al. Chromosome abnormalities and genetic counseling Oxford, 2004, 577 s.. Oxford, 2004.
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Kočárek E. Genetika Scientia, Praha, 211 s. 2008.
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ŘEHOUT V. a kol. Genetika I.. JU ZF, 256 s., 2000.
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Snustad D.P. et al. Genetika. 2. vydání, překlad MU Brno, 2017, 844 s. ISBN 9788021086135. MU Brno, 2017. ISBN 9788021086135.
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Studijní pomůcky. prezentace jsou k dispozici na webových strínkách katedry.
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