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Lecturer(s)
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Vaněk Daniel, RNDr. Ph.D.
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Věchtová Pavlína, RNDr. Ph.D.
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Doležal Tomáš, doc. Mgr. Ph.D.
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Course content
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Content of lectures: " Definitions, introduction to the field of application of molecular biology into the forensic genetics. " Quantity, quality, and specific features of DNA in the context of forensic genetics " Biological stains, their preservation and processing " Crime scene examination, sampling, unspecific and specific body fluid examination " Polymorphic loci and repetitive sequences on autosomes. " Lineage markers on Y-chromosome and mtDNA " Database evaluation of the forensic genetics results " Statistical evaluation of the forensic genetics results " The power of DNA based evidence " Identification of the victims of mass fatalities and war conflicts using DNA based identification of skeletal remains " DNA legislation in Czech Republic and abroad " Certification, accreditation, quality assurance " Archaeogenetics and genetic genealogy as special methods in forensic genetics Content of practicals: " Unspecific and specific body fluid examination " Microscopic hair analysis " DNA extraction, quantitation, amplification and fragment analysis " Statistical evaluation of the results
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Learning activities and teaching methods
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Monologic (reading, lecture, briefing), Dialogic (discussion, interview, brainstorming), Demonstration, Laboratory
- Class attendance
- 35 hours per semester
- Preparation for classes
- 30 hours per semester
- Preparation for exam
- 40 hours per semester
- Semestral paper
- 50 hours per semester
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Learning outcomes
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The main objective is to introduce the field of forensic genetics to the auditorium. The lectures will cover all areas of the process of the identification of biological material not only from the methodological point of view but also quality assurance and legal aspects. Students will have a chance to solve their own monk cases and try some basic sampling procedures as well as the examination of body fluids and the use of DNA databases.
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Prerequisites
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unspecified
KMB/608
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Assessment methods and criteria
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Oral examination, Test, Development of laboratory protocols
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Recommended literature
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Butler J., Advanced topics in Forensic DNA typing: Methodology, 2011, Academic Press Elsevier.
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Butler J., Fundamentals of Forensic DNA Typing, 2009, Academic Press Elsevier.
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Fung W.K., Statistical DNA Forensics, 2008, Wiley.
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Články z věd. časopisů:. Croatian Medical Journal.
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Články z věd. časopisů:. Forensic Science International: Genetics.
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Články z věd. časopisů:. International Journal of Legal Medicine.
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Články z věd. časopisů:. Investigative Genetics.
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Články z věd. časopisů:. Journal of Forensic Sciences.
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