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Vyučující
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Bumba Jakub, Ing. Ph.D.
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Štys Dalibor, prof. RNDr. CSc.
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Štysová Rychtáriková Renata, Ing. Bc. Ph.D.
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Obsah předmětu
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Structure, Formulas and Nomenclature of Organic Compounds: Graphic Representations and Nomenclature (trivial and IUPAC). Hydrocarbons: alkanes, alkenes, alkynes, aromatics. Nomenclature, phys-chem. properties and chemical reactions, hydrocarbons as natural substances, Functional groups: Halogenated compounds. Oxygen, nitrogen and sulfur derivatives, organometallic compounds, phys-chem. properties, reaction of individual functional groups, production and significance of derivatives, their occurrence and importance in nature: Carbohydrates: Structure and properties of monosaccharides; Disaccharides; polysaccharides, carbohydrate derivatives. Lipids: Structure and properties. Esters and other lipids, phospholipids, sphingolipids, biomembranes. Steroids: Structure of Steroids; Sterols; Bile acids; Steroid hormones; Cardiotonic steroids; Amino acids, biologically important amines. Peptides. Proteins. UV-VIS spektroskopie, IČ a Ramanova spektroskopie, MS spektrometrie, NMR spektroskopie Hlavní databáze organických sloučenin, hlavní software pro práci se vzorci a strukturami, databáze metabolických drah. V rámci praktik pak ozřejmění vztahu mezi spektrem, strukturou a interakcemi látek
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Studijní aktivity a metody výuky
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Monologická (výklad, přednáška, instruktáž), Dialogická (diskuze, rozhovor, brainstorming), Laboratorní práce
- Účast na výuce
- 98 hodin za semestr
- Semestrální práce
- 40 hodin za semestr
- Domácí příprava na výuku
- 10 hodin za semestr
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Výstupy z učení
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The aim of lectures in Chemistry II is to provide students with an overview of the following topics: 1) Nomenclature of organic compounds, structure of organic compounds and their principles, main chemical reactions of individual groups of substances, 2) Software for drawing, displaying and optimizing of chemical structures, databases of organic compounds, databases of metabolic pathways, basics of work with profesional literature 3) Main types of spectroscopy in organic chemistry and the relationship between structure and spectrum. In the framework of practical exercises: a) Students who have not completed extensive laboratory work in the previous study will acquire the principles of working with laboratory techniques in a chemical laboratory, b) all students undergo exercises to illustrate the relationship between the structure of the molecule, its interactions and the degree of ionization and the spectrum in the UV and visible areas
Graduates will achieve basic knowledge in the subject of physico-chemical properties of organic compounds, they will be familiar with systematical and trivial nomenclature and due to practical excercises in laboratory the absolvents will gain elementary skills in the field of laboratory research. Absolvents will get on necessary theoretical and practical background for the follow-up chemistry-based courses in Hydrochemistry and Biochemistry.
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Předpoklady
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This course is continuation of general and inorganic chemistry course ( Chemistry I), thus the pre-requisite is to pass the course Chemistry I.
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Hodnoticí metody a kritéria
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Písemná zkouška, Analýza výkonů studenta
Participation on lectures is optional Exercise part 1 - basics of organic chemistry, participation is compulsory until passing the credit test. Exercise part 2 - presentation of colloquial work, attendance compulsory, apologies are accepted from students in practice, students with confirmation from a doctor or having other serious reasons for non-attendance accepted by the teacher To pass the course successfully, the student must: 1) Participate in excercises 2) Write a credit test to get a credit. To get the credit, 95% of the questions need to be answered correctly. 3) Present a seminar lecture with content determined by the teacher 4) Participate in laboratory practice 5) Submit and get approval of the laboratory practice protocol. 3) Pass the examination of organic molecules spectra analysis. Only students who pass the credit test and give a seminar lecture will be admitted. Exam and credit will be enrolled for students after successful approval of the laboratory practice protocol.
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Doporučená literatura
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NIST webook chemistry. 2018.
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John Mc Murry. Organická chemie. Praha, VŠCHT, 2007.
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Petr Šimůnek. Organická chemie 1 (pro posluchače kombinovaného studia oboru Speciální chemickobiologické obory). Pardubice.
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University of Liverpool. ChemTube 3D. Liverpool, 2018.
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